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Chlorambucil (Leukeran)

This drug has been around since 1961. It is a very well tolerated medication which comes in oral tablet form. It can be used in a variety of schedules, such as daily for a few weeks, or at higher doses for a few days only, and then repeated every few weeks. It is most commonly used in treatment of the following cancers:

• Chronic Lymphocytic Leukemia

• Lymphomas

• Ovarian

Leukeran is given mostly in conjunction with Prednisone. The type and extent of a cancer will determine the method and schedule of administration of this drug. This decision is made by the medical oncologist. Chlorambucil is normally administered daily for a number of days.

Side Effects:

The degree and severity of the side effects depend on the amount and schedule of the administration of Chlorambucil. Following are some of the most common and significant ill effects:

• Low white blood counts

• Low platelet count

• Anemia

• Hair Loss

• Lung damage

It is imperative that patients relay any side effects or problems to their medical oncologist.