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Zinecard (Dexrazoxane)

When used in high doses, certain chemotherapy drugs can cause a damage to the heart muscle.  These drugs are:

• Adriamycin

• Daunorubicin

• Mitoxantrone

The dosage as well as schedule of these drugs is an important factor as to the degree of the damage to the heart.  Many drugs, as well as natural substances have been used to reduce the extent of heart damage from these medications.  Zinecard seems to be able to reduce the severity of heart damage from the above mentioned medicines. so that they could be used safely and may be at a higher doses.